GASB

Prof. Dr. Michael Bott

Institute of Bio- and Geosciences, IBG-1: Biotechnology Forschungszentrum, Jülich GmbH, 52425, Jülich, Germany

 

Talk: Genetically encoded biosensors – valuable tools for white biotechnology

Microorganisms have evolved a large repertoire of sensors that enable them to detect and respond to their environment. Typical representatives of such sensors are for example one-component transcriptional regulators, two-component signal transduction systems or serine/threonine protein kinases. In recent years, these sensors were employed as “biobricks” to construct devices that enable tackling of numerous challenges in white biotechnology. I will describe examples for the design and application of transcription factor-based biosensors in microbial strain and enzyme development and for the use of two-component systems as basis for technical biosensors.